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Alaa Alachkar Selected Research

Histamine H3 Receptors (Histamine H3 Receptor)

1/2021Ameliorating effects of histamine H3 receptor antagonist E177 on acute pentylenetetrazole-induced memory impairments in rats.
12/2020Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease.
3/2020Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats.
11/2019The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats.
1/2019Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats.
1/2017The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats.

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Alaa Alachkar Research Topics

Disease

6Epilepsy (Aura)
01/2021 - 01/2018
3Memory Disorders (Memory Loss)
03/2020 - 01/2017
2Amnesia (Dissociative Amnesia)
12/2020 - 01/2019
2Alzheimer Disease (Alzheimer's Disease)
12/2020 - 01/2017
2Seizures (Absence Seizure)
01/2020 - 10/2018
1Neuralgia (Stump Neuralgia)
12/2020
1Cognitive Dysfunction
03/2020
1Status Epilepticus (Complex Partial Status Epilepticus)
11/2019
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019

Drug/Important Bio-Agent (IBA)

6Histamine H3 Receptors (Histamine H3 Receptor)IBA
01/2021 - 01/2017
4Anticonvulsants (Antiepileptic Drugs)IBA
03/2020 - 01/2018
3Dizocilpine Maleate (Dizocilpine)IBA
12/2020 - 01/2017
3Pentylenetetrazole (Metrazol)IBA
03/2020 - 10/2018
3Neurotransmitter Agents (Neurotransmitter)IBA
03/2020 - 01/2019
3imidazoleIBA
01/2019 - 01/2018
2Histamine (Histamine Dihydrochloride)FDA Link
03/2020 - 10/2018
1Analgesics (Analgesic Drugs)IBA
12/2020
1LigandsIBA
12/2020
1CatalaseIBA
03/2020
1Aminobutyrates (Aminobutyric Acid)IBA
03/2020
1EsterasesIBA
03/2020
1gamma-Aminobutyric Acid (GABA)IBA
03/2020
1Glutathione (Reduced Glutathione)IBA
03/2020
1Malondialdehyde (Propanedial)IBA
03/2020
1Acetylcholine (Acetylcholine Chloride)FDA Link
03/2020
1Superoxide DismutaseIBA
03/2020
1Proto-Oncogene Proteins c-fos (FRAs)IBA
03/2020
1Glutamic Acid (Glutamate)FDA Link
03/2020
1Neuroprotective AgentsIBA
11/2019
1Pilocarpine (Ocusert)FDA LinkGeneric
11/2019
1Scopolamine (Hyoscine)FDA Link
01/2017
1zolantidineIBA
01/2017
1Donepezil (Aricept)FDA LinkGeneric
01/2017
1pitolisantIBA
01/2017
1Pyrilamine (Mepyramine)FDA Link
01/2017

Therapy/Procedure

2Therapeutics
12/2020 - 01/2020